IgG4-related disease simulating Hodgkin lymphoma in a child

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IgG4-related inflammation of the orbit simulating malignant lymphoma.

Immunoglobulin (IgG) 4-related disease is characterized by elevated serum IgG4 and tissue infiltration by IgG4-positive plasma cells. We report a case of IgG4-related inflammation of the orbit simulating extranodal marginal zone B-cell lymphoma (EMZL). A 72-year-old female complained of bilateral eyelid swelling for three years. A MRI scan demonstrated two kinds of lesions, tumor 1, presenting ...

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Hodgkin Lymphoma and Anaplastic Variants of Non-Hodgkin Lymphoma

  Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...

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IgG4-Related Perineural Disease

Aims. To elucidate characteristics of IgG4-related disease involving the peripheral nervous system. Methods. Retrospective review of 106 patients with IgG4-related disease identified 21 peripheral nerve lesions in 7 patients. Clinicopathological and radiological features were examined. Results. Peripheral nerve lesions were commonly identified in orbital or paravertebral area, involving orbital...

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ژورنال

عنوان ژورنال: Human Pathology: Case Reports

سال: 2016

ISSN: 2214-3300

DOI: 10.1016/j.ehpc.2015.08.002